I'm playing and loving it! If you don't own it and enjoyed TDU 1 I strongly recommend it, really nice MMO racing game! Buy it on Direct2Drive.com with 20% discount using this link (copy the discount code and paste it into Promotion code field at Checkout page)
If you have a CrossfireX system you may already noticed that current Catalyst lacks a proper CrossfireX profile for TDU 2. After doing some tests I found that using Bioshock CrossfireX profile and setting MVPUMode to Alternate Frame Rendering actually improved CrossfireX usage a bit.
A Guru3D user posted some screenshots comparing framerate, using RadeonPro he gained about 35% more performance. A bit shy result but better than nothing until AMD figure out a better way to scale multi-GPU on TDU2.